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Cub domain-containing protein

WebDec 9, 2010 · CDCP1 Is Up-Regulated in Highly Metastatic Melanoma Cell Lines. CDCP1, also known as SIMA135 or Trask, is a transmembrane glycoprotein that contains three putative extracellular CUB domains. CUB domains are believed to function in protein–protein ( 22, 23) and protein/carbohydrate ( 24) interactions. We initially … WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. CDCP1 has also been designated as CD318 (cluster of differentiation …

Inhibition of CDCP1 by 8-isopentenylnaringenin synergizes with …

WebFeb 15, 2024 · CUB domain containing protein 1 (CDCP1), also known as Trask, gp140, SIMA135, and CD318, is a type I single-pass membrane protein that is highly overexpressed in a variety of solid tumors (12 – 14). WebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological conditions and healthy women and in a number of other cancer … hausdata jansen gmbh https://salermoinsuranceagency.com

CUB-domain-containing protein 1 overexpression in solid …

WebJul 10, 2012 · The deduced 993-amino acid protein has an N-terminal signal sequence, followed by 9 putative calcium-binding EGF-like repeats, a spacer region, and a C-terminal CUB domain. The spacer region contains 5 potential N-glycosylation sites. SCUBE3 was predicted to be secreted as a mature 971-amino acid protein with a calculated molecular … WebDec 3, 2012 · Specific cleavage of the transmembrane molecule, CUB domain-containing protein-1 (CDCP1), by plasmin-like serine proteases induces outside–in signal transduction that facilitates early stages of ... WebSep 1, 2009 · CUB and sushi domain-containing protein 3. Alternative names. CUB and sushi multiple domains protein 3; Gene names. Name. CSMD3. Synonyms. KIAA1894. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. Taxonomic lineage. hauser lola astanova

Structural Requirements for Cub Domain Containing Protein 1

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Cub domain-containing protein

UniProt

WebMar 28, 2011 · Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is a secreted glycoprotein that is overexpressed in lung cancer tumor tissues and is correlated with the invasive ability in a lung ... WebMay 21, 2024 · The role of CDCP1 (CUB domain-containing protein 1) and ADAM12 (a disintegrin and metalloproteinase 12) in ovarian cancer. J BUON. 2015;20(3):673–679. 16. Miura S, Hamada S, Masamune A, et al. CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells.

Cub domain-containing protein

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WebMay 21, 2024 · CUB domain-containing protein-1 (CDCP1) is a transmembrane protein that contains three extracellular CUB domains and acts as a substrate for Src family … WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). CDCP1/Trask is a 140kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two …

WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and … WebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological …

WebMedChemExpress References: PMID: 37013960 CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) resistance by regulating EGFR signaling pathways and is a potential target in lung Cancer treatment. This study aims to identify a CDCP1 reducer that synergistically … WebThe appearance of synapses was a crucial step in the creation of the variety of nervous systems that are found in the animal kingdom. With increased complexity of the organisms came a greater number of synaptic proteins. In this review we describe synaptic proteins that contain the structural domains CUB, CCP, or TSP-1. These domains are found in …

WebSummary. This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis.

WebNational Center for Biotechnology Information hausboot mieten dänemark ostseeWebDec 9, 2010 · Using such approaches, we identified CUB-domain–containing protein 1 (CDCP1) as a membrane protein that is up-regulated in highly metastatic melanomas. … hausen taunusWebOct 2, 2024 · Comment: annotation includes both PSPI/PSPII interaction residues highlighted. Download Cn3D for Viewing 3D Structure Scroll to Sequence Alignment … hauschka skin tonerWebMar 2, 2015 · The transmembrane glycoprotein, CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein 1 (CDCP1) is overexpressed in several cancer types and is a predictor of poor prognosis for patients ... haushalt spitex krankenkasseWebMar 23, 2024 · The structure of CUB domains consists of a beta-sandwich with a jelly-roll fold. Almost all CUB domains contain four conserved cysteines that probably form two … haushaltsetikettenWebCUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix degradation during tumor invasion and metastasis in a tyrosine phosphorylation-dependent manner. hauser pistolWebMay 5, 2024 · We here demonstrate that the CUB-like-domain containing protein RBT-1 acts as a functional receptor of Cry6A, which mediates the intestinal cell interaction and … haushaltsutensil 11