Web3 jan. 2024 · nucleotide excision repair: a DNA repair mechanism that corrects damage done by UV radiation, including thymine dimers and 6,4 photoproducts that cause bulky distortions in the DNA Errors during Replication DNA replication is a highly accurate process, but mistakes can occasionally occur as when a DNA polymerase inserts a wrong base. WebIt is a type of long patch excision repair mechanism. It distorts the configuration of the DNA helix. NER mainly repairs the DNA damage that originated due to the exogenous mutagens. NER repairs the damage induced by the UV-light in a DNA, oxidative damage and large chemical adducts. Requirements
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5.13: DNA Repair - Biology LibreTexts
Web14 mei 2024 · 5.13: DNA Repair. DNA in the living cell is subject to many chemical alterations (a fact often forgotten in the excitement of being able to do DNA sequencing on dried and/or frozen specimens). If the genetic information encoded in the DNA is to remain uncorrupted, any chemical changes must be corrected. WebA mutation that causes a change in a single nucleotide in DNA. A) Will have no effect on the resulting protein. =B) Changes the corresponding nucleotide in mRNA, resulting in a … WebThe repair enzymes replace abnormal bases by making a cut on both the 3' and 5' ends of the damaged base ( Figure 14.19 ). The segment of DNA is removed and replaced with the correctly paired nucleotides by the action of DNA pol. Once the bases are filled in, the remaining gap is sealed with a phosphodiester linkage catalyzed by DNA ligase. how stain concrete floors