WebOct 11, 2013 · Klotho is expressed in the retina and is important for healthy retinal function. Although the mechanisms for the observed abnormalities are not known, they are … WebKlotho蛋白(KL)检测试剂盒(化学发光免疫分析法) J117660 CLIA Kit for Klotho (KL) 96T Homo sapiens (Human) *受体1(FOLR1)检测试剂盒(化学发光免疫分析法) J117661 CLIA Kit for Folate Receptor 1, Adult (FOLR1) 96T Homo sapiens (Human)
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WebNov 17, 2024 · Three primary isoforms of the α-Klotho protein have been identified as follows: (1) the full-length transmembrane form (mKl), (2) a shed soluble form [soluble klotho (sKl)], and (3) a secreted truncated form that is produced by alternative splicing of klotho mRNA and consists of KL1 only ( 17, 18 ). WebDec 1, 2024 · Klotho overexpression reduces hippocampal neuron loss and exhibits neuroprotective effects as well as anti-cognitive impairment functions in CNS diseases … martin luther king\\u0027s assassination
Circulating Levels of Soluble Klotho and FGF23 in X-Linked ...
WebJun 14, 2024 · The klotho (KL) family of genes includes α-klotho, β-klotho and γ-klotho [], which are all translated as single-pass transmembrane proteins. α-klotho is highly expressed in the brain and kidney, and to a lesser extent in other organs [].In the periphery, transmembrane α-klotho acts as a co-receptor for FGF23 to increase binding affinity to … WebJan 18, 2024 · The present study investigated the effects of klotho overexpression and knockdown by an intracerebroventricular injection of a lentiviral vector that encoded … WebNov 1, 2010 · Context: Circulating fibroblast growth factor (FGF)-23 is variably elevated in individuals with X-linked hypophosphatemia (XLH), and klotho has recently been shown to effect renal phosphate handling, yet limited data are available on circulating FGF23 and klotho in XLH. Objective: The objective of the study was to characterize circulating FGF23 … martin luther king\u0027s most famous speech