Tīmeklis2024. gada 13. okt. · Oas1i 2 ' -5 ' oligoadenylate synthetase 1I [ (Norway rat)] Gene ID: 304507, updated on 13-Oct-2024. Summary. Predicted to enable 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Predicted to be involved in defense response to virus; negative regulation of viral genome replication; and … Tīmeklis2011. gada 6. sept. · Introduction. Hypoxia-inducible factor (HIF)-1α is a transcription factor that has been associated recently with the progression of chronic renal injuries. 1 – 4 HIF-1α is upregulated in different chronic kidney diseases. 1 – 3,5,6 HIF-1α is also shown to stimulate collagen accumulation by activating fibrogenic factors such as …
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TīmeklisObjectives: Our previous study showed that resveratrol (Res) attenuates apoptosis and mitochondrial dysfunction in alveolar epithelial cell injury induced by hyperoxia by … TīmeklisConsequently, activation of PGC-1α by nicotinamide restored BPA-mediated cognitive deficits in rats. Results suggest that the treatment of nicotinamide has therapeutic potential and rescues BPA-mediated neuronal death and cognitive deficits by upregulating the PGC-1α and GFER-DRP1 link, thus balancing mitochondrial … filled button round corner flutter
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Tīmeklis2013. gada 1. jūn. · About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press … Tīmeklis2013. gada 29. janv. · Rats were deeply anaesthetized (120 mg/kg pentobarbital) and perfused transcardially with 100 ml of normal saline, followed by 200 ml of 4% paraformaldehyde in 0.01M phosphate buffer, pH 7.4. Brains were post fixed for 24 h in 4% paraformaldehyde and cryopreserved in 20% and 30% sucrose in phosphate … TīmeklisSirtuin 1 alleviates microglia-induced inflammation by modulating the PGC-1α/Nrf2 pathway after traumatic brain injury in male rats Brain Res Bull . 2024 Jul;185:28-38. … grounded game site