WebOct 19, 2024 · Because RNF8 is an E3 ligase, we attempted to investigate whether it could ubiquitinate Akt. An in vivo ubiquitination assay was performed using endogenous Akt immunoprecipitation or nickel-nitrilotriacetic acid (Ni-NTA) pull-down under denaturing conditions. The results revealed that Akt ubiquitination was dramatically increased by the … WebWe also showed that RNF8 and RNF8 ubiquitination activity are needed for efficient localization of Nbs1 to DSBs. More specifically,wedemonstratedthatRNF8-mediatedubiquitina-tion of Nbs1 contributes significantly to Nbs1 localization to DSBs.ByusingEGFP-basedDSBrepairsubstrates,wedemon-strated that RNF8 is important …
泛素连接酶表 Cell Signaling Technology
Web一、RNF8,全称 ring finger protein 8,是近年发现的一种 DNA损伤应答蛋白。它包含 485 个氨基酸残基,在人体组织中广泛表达,是一种含有 FHA 及 RING 结构域的 E3 泛素连接酶]。 Web丁香通为您找到118条rnf8信息,包括rnf8报价行情,优质供应商,图片,品牌等最新信息,丁香通为买家提供用户服务,诚信保障等服务,批发采购rnf8,上丁香通。 terra buy the dip
Nrf2相关知识普及 - 百度文库
WebSμ–Sγ1 junctions in RNF8-deficient B cells have increased microhomology: 34% of the junctions have 0 or 1 bp identity in rnf8−/− cells, compared to 61% of WT cells. Also, 24% of junctions in the KO cells have insertions that are ≥ 2 bp, compared to 7% of the WT junctions ( Santos et al., 2010 ). WebChemicalBook 为您提供RNF8抗体的化学性质,熔点,沸点,密度,分子式,分子量,物理性质,毒性,结构式,海关编码等信息,同时您还可以浏览RNF8抗体产品的价格,供应 … WebNrf2(NF-E2-related factor 2)是细胞氧化应激反应中的关键因子,受Keap1的调控,通过与抗氧化反应元件ARE(antioxidant response element)相互作用,调节抗氧化蛋白和II相 … trick tower