Web18 Jun 2024 · Speckle-type POZ protein (SPOP) is also implicated in regulating genomic stability ( 29 – 31 ); however, how SPOP controls genomic stability is unclear. In the present study, we show that SPOP functions as an E3 ubiquitin ligase that binds to 53BP1 primarily during S phase and catalyzes K29-linked polyubiquitination of 53BP1. Web1 Oct 2024 · Moreover, this is the first time quantitative features learned from patient genetics and histology have been used for content-based image retrieval, finding similar …
Gabriella Levin - Försäljning - SPOP/ Swedish Performance
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scipy.optimize.minimize — SciPy v1.10.1 Manual
WebSAP Learning offers free online courses for anyone who wants to build in-demand development skills and prepare for SAP Certifications. Find out more! Web23 Jan 2024 · Scientists have captured the 3D structure of SPOP, revealing how mutations in previously unappreciated regions fuel cancer. FULL STORY. SPOP is the most mutated … Web27 Oct 2015 · The identity of the affected genes suggested that SPOP affects DNA repair pathways. Further investigation in human and mouse models confirmed that mutant SPOP blocks a process called called homology–directed repair: this is the method that cells normally use to repair double-stranded DNA breaks. ohio department of medicaid infant mortality