WebApr 23, 2009 · Individuals with the functional TRIB3 Q84R polymorphism are at risk for MetS. The TRIB3 R84 allele especially predisposes to carotid atherosclerosis in part through the effects of abdominal obesity, hypertriglyceridemia, and insulin resistance. WebDec 23, 2024 · As a stress sensor, pseudokinase Tribble 3 (TRIB3) responds to multiple stressors and participates in chronic inflammation, metabolism and malignant diseases by interacting with signal transduction proteins and functional proteins. 14, 24 A recent study reported that TRIB3 impairs the degradation function of autophagy and the proteasome …
TRIB3 is induced through the PERK/ATF4/CHOP pathway of
WebApr 12, 2024 · TRIB3 promotes chronic inflammation and cancer by interacting with intracellular signaling and functional proteins. The interaction of TRIB3 and the … WebApr 1, 2024 · The functional difference between TRIB pseudokinases in these systems is further highlighted by their differential expression in hemopoietic cells , with TRIB2 … google docs referencing
Persistent epigenetic alterations in transcription factors after a ...
WebMar 29, 2024 · TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis. Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring … WebDec 9, 2024 · To test whether expression of T58A alleviates the dependence of MYC function and gene expression on TRIB3, we applied CRISPR/Cas9 technology to establish … WebThe aberrant methylation of 3 TFs (KLF4, RUNX1, and RORA) have been well described in cancers that suggested critical functions in carcinogenesis. 32-34 Both DNA … chicago housewares show 2020